Radioprotector Compounds

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Categories: “Neurological Disorders

Reference #: 2012-030

OTC Contact: Ruchika Nijhara, Ph.D., MBA, CLP (Directory Information | Send a Message)


Radioprotector agents are used in the diagnostics and therapeutic settings to protect normal (e.g., non-cancerous) tissues or cells from radiation damage. These agents are also used as a means of protection in the setting of radiation exposure to the normal population. However, current commercially available radioprotectors are generally too toxic or are insufficiently active to be clinically useful. The present invention describes radioprotector compounds that are safe and effective for protection against ionizing radiation.


The compounds described in the present invention can be used as radioprotectors in the following settings:


Stage of Development

In-vivo studies demonstrate that the compounds can effectively protect rats and mice against ionizing radiation. Furthermore, Georgetown researchers have identified the mechanism of action of these compounds. They are currently studying the optimal dose schedule for these compounds for protection against total body irradiation.

Relevant Publications

Manuscript under preparation.

Patent Status

Patent application pending