Genetic Marker and/or Biomarkers for Traumatic Brain Injury, and Ultrasensitive Assays for Biomarkers of Traumatic Brain Injury

Categories:  “Neurological Disorders” “Diagnostics

Reference #: 2017-042

OTC Contact: Ruchika Nijhara, Ph.D., MBA, CLP (Directory Information | Send a Message)


This invention provides an ultrasensitive assay for GFAP and other biomarkers of TBI to accurately detect or measure biomarkers of mild, moderate and severe TBI. Further, it provides a means to monitor or prevent sequelae of TBI, helping to triage and guide the treatment of TBI afflicted individuals of varying severity.


  • Accurate methods for diagnosing, prognosing, monitoring recovery from and assessing traumatic brain injury (TBI)


  • The assay can be combined with APOE4+ allele screening for improved diagnosis, prognosis, and monitoring of recovery

Stage of Development


Patent Status

IP protected.


Mark Burns