Method for Identification of Relapse Risk and Treatment in Patients with Colorectal Cancer

Quick Links

Disclose Your Invention
MTA/CDA Assistance
Technologies for Licensing
Industry Collaboration Opportunities
Research and Clinical Trials
Education Links
Office of Sponsored Research

Categories: “Cancer Therapeutics

Reference #: 2014-004

OTC Contact: Ruchika Nijhara, PhD, MBA, CLP (Directory Information | Send a Message)


Method of predicting recurrence of colorectal cancer by measuring a combination of six microRNAs (miRNAs) taken from a patient samples, where evaluating the hierarchical clustering of the six circulating miRNAs indicates the risk of cancer recurrence.

The miRNA panel provides reliable and distinctive signatures for identifying the organ source of metastases. The expression levels of specific miRNAs in the tissues correlate with the probability of recurrence-free survival and through multivariate analysis show that perturbed expression of miRNAs in colon cancer has prognostic potential.



Stage of Development

Validated across 30 patients, currently investigators are increasing sample population size and bio-
specimen source.

Patent Status

Patent application is pending.