Biomarkers for Diagnosis and Prognosis of Thyroid Cancer

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Categories:  “Cancer Therapeutics

Reference #: 2012-005

OTC Contact: Ruchika Nijhara, Ph.D., MBA, CLP (Directory Information | Send a Message)

Description

Researchers at Georgetown University have identified a novel panel of microRNAs that could be used for
the diagnosis, prognosis, and treatment of thyroid cancer. The invention relates to using a combination of miRNAs to diagnose thyroid cancer, as well as to discriminate between different types of thyroid cancers. The present invention provides a method for screening for a specific type of thyroid cancer or precancerous lesion, including papillary carcinoma, follicular carcinoma, follicular adenoma, and nodular hyperplasia.

Application

Advantages

Stage of Development

miRNA expression profiles were determined for normal tissue and different types of thyroid tumors and
lesions. This work is currently being extended to additional types of cancers.

Patent Status

Provisional application filed.

Inventor Status